Articles Tagged With:
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The Best Treatment for Heavy Menstrual Bleeding
This randomized controlled trial among 62 individuals compared the 52-mg levonorgestrel intrauterine device to combined oral contraceptives for heavy menstrual bleeding and found that, in the intention-to-treat analyses, there was no significant difference in Menstrual Bleeding Questionnaire scores at six months or 12 months (mean difference, 2.5; 95% confidence interval [CI], -10.0, 5.0; and mean difference, -1.1; 95% CI, -8.7, 6.5, respectively).
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Why It Is Worth Making Sure All Your Pregnant Patients Receive the Influenza Vaccine
Infants younger than 6 months of age are at risk for severe influenza infections. Vaccination during pregnancy reduces infection and hospitalization risk by nearly 70%.
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Respiratory Syncytial Virus Infection During Pregnancy
Although women who developed respiratory syncytial virus (RSV) infection during pregnancy had a higher risk of preterm birth compared to those without RSV infection, the risk of miscarriage, stillbirth, low birth weight, and small for gestational age fetus were similar between the RSV and placebo groups.
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Globally Connected and Universally at Risk: Mosquito-Borne Diseases in the 21st Century
Climate change has altered and expanded the geographical distribution for key vectors of travel-related and mosquito-borne illnesses, making some of these diseases endemic to areas where they were absent in the recent past. Therefore, it is imperative that emergency practitioners become familiar with travel-related and global illnesses, their geographical prevalence, current epidemiologic trends, clinical presentations, and emergency management.
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Sickle Cell Disease in the Emergency Department
Sickle cell disease is a complex condition with diverse potential complications. In the emergency department setting, physicians should be aware of the life-threatening pathologies that can affect patients with sickle cell disease.
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Electrophysiology, Muscle Ultrasound, and MRI in the Diagnosis of Neuromuscular Disorders
To accomplish accurate diagnosis of nerve and muscle disorders, clinical collaboration with ultrasound and magnetic resonance imaging experts is invaluable and can provide critically important information beyond electrophysiology.
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Metformin Use Is Associated with Decreased Diabetes-Associated Dementia
In two recent cohort studies, metformin use was found to decrease the risk of developing dementia in older adults with type 2 diabetes mellitus.
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Adverse Neurological Events from Immune Checkpoint Inhibitors
Immune checkpoint inhibitors have transformed the natural history of many metastatic cancers and now are widely used. However, the activation of killer T-cells also has caused serious, often fatal complications from the treatment. The central nervous system is a common victim of these complications.
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What Is the Best First-Line Treatment for Young Women with Generalized Epilepsy?
Valproate is a highly efficacious drug for treating idiopathic generalized epilepsy (IGE) but is not an option for many young women because of known teratogenic risks. This retrospective, multicenter study examined women with IGE who were treated initially with either levetiracetam or lamotrigine monotherapy, demonstrating superior efficacy of levetiracetam, although exclusively in women with juvenile myoclonic epilepsy.
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Searching for Step Counts: Defining Goals for Daily Exercise
A systematic review and meta-analysis of studies of the association of step counts and cadence with all-cause mortality and cardiovascular events showed the benefits in these outcomes are statistically significant, at about 2,600 steps/day and peak at about 8,000 steps/day. Also, faster step cadence augments these benefits.